The principle behind this lies in the basic laws of physics and physiology, particularly Henry's Law and Boyle's Law:

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Being between 1.2 to 1.5 ATM in a hyperbaric chamber increases the pressure around an individual, which in turn has an effect on gases, including oxygen. According to Henry's Law, the amount of gas that dissolves in a liquid is proportional to the partial pressure of that gas exerted on the surface of the liquid. In simpler terms, when the atmospheric pressure increases, as it does in a hyperbaric chamber set to between 1.2 - 1.5 ATM, more oxygen from the air (or from an added oxygen source) can dissolve into the bloodstream.

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Under normal atmospheric conditions, oxygen is primarily transported throughout the body bound to hemoglobin in red blood cells. With the increased pressure in a hyperbaric chamber, oxygen dissolves directly into all of the body's fluids, including the blood plasma, cerebrospinal fluid, and lymph fluid. This means that even areas of the body that might have reduced circulation, or areas where blood flow might be diminished or blocked, can still receive higher concentrations of oxygen.

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This enhanced oxygen saturation in the body's tissues can support healing, reduce inflammation, and provide other potential therapeutic effects.