TB-500

TB-500 is a synthetic peptide derived from Thymosin Beta-4, a naturally occurring protein involved in cell migration, wound healing, and inflammation modulation. TB-500 is strictly used for laboratory research purposes, particularly exploring its potential biological activities relating to tissue repair and inflammatory responses.

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Overview of TB-500 Research

Composition and Origin

• Synthetic Peptide: TB-500 is a lab-synthesized segment of Thymosin Beta-4, a protein naturally present in most mammalian tissues (Goldstein et al., 2012).

• Research-Oriented Use: Explicitly designated for laboratory research purposes only, not approved for human use or therapeutic application.

Key Areas of Animal Research

• Tissue Repair and Regeneration: Animal studies have investigated potential roles in promoting faster tissue repair, regeneration processes, and overall cellular recovery (Philp et al., 2003; Sosne et al., 2004).

• Inflammation Modulation: Preclinical research has examined TB-500 for its potential effects in regulating inflammatory pathways in animal models, potentially supporting balanced inflammatory responses (Crockford et al., 2010).​

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Important Reminders for Research Use

• Sterile Handling: Ensure peptides are handled under sterile conditions to avoid contamination.

• Proper Storage: Keep refrigerated according to the provided storage guidelines.

• Acknowledgment of Use: By purchasing TB-500, you explicitly confirm and acknowledge that it is strictly intended for laboratory research and not approved or intended for human consumption or therapeutic use.

References:

• Goldstein, A.L., Hannappel, E., Kleinman, H.K. (2012). Thymosin beta4: actin-sequestering protein moonlights to repair injured tissues. Trends in Molecular Medicine, 18(1), 9-12.

• Philp, D., Huff, T., Gho, Y.S., Hannappel, E., Kleinman, H.K. (2003). The actin binding site on thymosin beta4 promotes angiogenesis. FASEB Journal, 17(14), 2103-2105.

• Sosne, G., Hafeez, S., Greenberry, A.L., Kurpakus-Wheater, M. (2004). Thymosin beta4 promotes human corneal epithelial cell migration. Investigative Ophthalmology & Visual Science, 45(4), 1095-1100.

• Crockford, D., Turjman, N., Allan, C., & Angel, J. (2010). Thymosin beta4: structure, function, and biological properties supporting current and future clinical applications. Annals of the New York Academy of Sciences, 1194(1), 179-189.

Disclaimer:
TB-500 is intended strictly for research purposes only and has not been evaluated by the FDA. It is not approved for human consumption or therapeutic use. No claims are made regarding its effectiveness in diagnosing, treating, curing, or preventing any disease or medical condition. All research cited refers exclusively to preclinical animal studies.